Cascara sagrada, also known as Rhamnus purshiana, is a natural herb that has been used for centuries as a laxative, it is a key ingredient that makes Nature Reigns' Colon Cleanse, the best colon cleanse. It is derived from the bark of the cascara sagrada tree, which is native to the Pacific Northwest region of the United States.

The colon, also known as the large intestine, is an essential part of the digestive system. It i...